| Gene Information | |
|---|---|
| Gene Name | IDOL |
| Organism | Homo sapiens (Human) |
| Gene Length | 445 |
| Protein Names | E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8WY64 |
| Gene Card | MYLIP |
| Uniprot ID | Q8WY64 |
| Pfam | PF00373; PF09379 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:10593918}. |
| Pharmacological Animal Models | 0.027303(Chimpanzee);0.029817(Mouse);0.001000(Rat);0.085714(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2YHN (X-ray 3.00A ) 2YHO (X-ray 2.10A ) 6QLY (X-ray 2.50A ) 6QLZ (X-ray 2.34A ) |
| DBSNP | rs9370867 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305|PubMed:14550572}. Cell membrane {ECO:0000269|PubMed:14550572}; Peripheral membrane protein {ECO:0000269|PubMed:14550572}. |
| Mouse PG classification | NA |
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