| Gene Information | |
|---|---|
| Gene Name | RFC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1148 |
| Protein Names | Replication factor C subunit 1 (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (DNA-binding protein PO-GA) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000035928 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P35251 |
| Gene Card | RFC1 |
| Uniprot ID | P35251 |
| Pfam | PF00004; PF00533; PF08519 |
| In ASD | no |
| Allosteric Prediction | yes (0.458288026) |
| Ortholog in Animals | Alpaca_ RFC1 ( ortholog_one2one ) Dog_ RFC1 ( ortholog_one2one ) GuineaPig_ RFC1 ( ortholog_one2one ) Macaque_ RFC1 ( ortholog_one2one ) Mouse_ Rfc1 ( ortholog_one2one ) Pig_ RFC1 ( ortholog_one2one ) Rat_ Rfc1 ( ortholog_one2one ) Rabbit_ RFC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Wide tissue distribution. Undetectable in placental tissue. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003178(Rat);0.042424(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2EBU (NMR - ) 2K6G (NMR - ) 2K7F (NMR - ) 6VVO (EM 3.40A ) |
| DBSNP | rs2066791 rs1057747 rs11932767 rs17335452 rs17288828 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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