| Gene Information | |
|---|---|
| Gene Name | ID3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 119 |
| Protein Names | DNA-binding protein inhibitor ID-3 (Class B basic helix-loop-helix protein 25) (bHLHb25) (Helix-loop-helix protein HEIR-1) (ID-like protein inhibitor HLH 1R21) (Inhibitor of DNA binding 3) (Inhibitor of differentiation 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000117318 ) 3 ( ENSG00000283060 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q02535 |
| Gene Card | ID3 |
| Uniprot ID | Q02535 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-0.901246566) |
| Ortholog in Animals | Alpaca_ ID3 ( ortholog_one2one ) Dog_ ID3 ( ortholog_one2one ) GuineaPig_ ID3 ( ortholog_one2one ) Macaque_ ID3 ( ortholog_one2one ) Mouse_ Id3 ( ortholog_one2one ) Pig_ ID3 ( ortholog_one2one ) Rat_ Id3 ( ortholog_one2one ) Rabbit_ ID3 ( ortholog_one2one ) |
| Ohnologs | ID2, ID1, ID4 |
| Paralogs | ID1, ID4, ID2 |
| Tissue | NA |
| Tissue Specificity | Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LFH (NMR - ) |
| DBSNP | rs11574 rs11542317 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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