Gene Information
Gene NameTAF7L
OrganismHomo sapiens (Human)
Gene Length462
Protein NamesTranscription initiation factor TFIID subunit 7-like (Cancer/testis antigen 40) (CT40) (RNA polymerase II TBP-associated factor subunit Q) (TATA box-binding protein-associated factor 50 kDa) (Transcription initiation factor TFIID 50 kDa subunit)
Target NameNA
Target TypeNA
Gene Age132 ( ENSG00000102387 )
Evolutionary StageOpisthokonta
AlphaFoldDBQ5H9L4
Gene CardTAF7L
Uniprot IDQ5H9L4
PfamPF04658
In ASDno
Allosteric Predictionno (-0.476330889)
Ortholog in AnimalsAlpaca_ TAF7L ( ortholog_one2one )
Dog_ TAF7L ( ortholog_one2one )
GuineaPig_ TAF7L ( ortholog_one2one )
Macaque_ TAF7L ( ortholog_one2one )
Mouse_ Taf7l ( ortholog_one2one )
Pig_ TAF7L ( ortholog_one2one )
Rat_ Taf7l2 ( ortholog_one2many )
Rat_ Taf7l ( ortholog_one2many )
Rabbit_ TAF7L ( ortholog_one2one )
OhnologsTAF7
ParalogsTAF7
Tissuetestis
Tissue SpecificityTestis-specific. {ECO:0000269|PubMed:11279525}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.003371(Rat);0.101115(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs5951328  rs147493489  rs35899692  rs41310729 
Subcellular location [CC]Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Cytoplasmic in spermatogonia and early spermatocytes (preleptotene, leptotene, and zygotene);
translocates into the nuclei of pachytene spermatocytes and round spermatids. {ECO:0000250}.
Mouse PG classificationNA
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