Gene Information
Gene NameICEN7
OrganismHomo sapiens (Human)
Gene Length943
Protein NamesCentromere protein C (CENP-C) (Centromere autoantigen C) (Centromere protein C 1) (CENP-C 1) (Interphase centromere complex protein 7)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ03188
Gene CardCENPC
Uniprot IDQ03188
PfamPF11699; PF15620; PF15622
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.012449(Chimpanzee);0.001000(Mouse);0.001990(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5LSJ  (X-ray  3.25A  5LSK  (X-ray  3.50A  6MUO  (EM  3.60A  6MUP  (EM  3.50A  6SE6  (EM  3.50A  6SEE  (EM  4.20A  6SEF  (EM  3.70A  7PII  (EM  2.68A  7QOO  (EM  4.60A  7R5R  (EM  2.44A  7YWX  (EM  12.00A  7YYH  (EM  8.90A 
DBSNP rs11250  rs1056787 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:17651496}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:17651496, ECO:0000269|PubMed:19482874, ECO:0000269|PubMed:21529714}. Chromosome, centromere {ECO:0000269|PubMed:9645950}. Note=Localizes exclusively in the kinetochore domain of centromeres. {ECO:0000269|PubMed:21529714}.
Mouse PG classificationNA
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