| Gene Information | |
|---|---|
| Gene Name | ICEN22 |
| Organism | Homo sapiens (Human) |
| Gene Length | 561 |
| Protein Names | Centromere protein T (CENP-T) (Interphase centromere complex protein 22) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96BT3 |
| Gene Card | CENPT |
| Uniprot ID | Q96BT3 |
| Pfam | PF15511; PF16171 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002101(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7QOO (EM 4.60A ) 7R5S (EM 2.83A ) 7YWX (EM 12.00A ) |
| DBSNP | rs12102580 |
| Subcellular location [CC] | Nucleus. Chromosome, centromere {ECO:0000269|PubMed:16716197, ECO:0000269|PubMed:19070575, ECO:0000269|PubMed:19412974}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:19412974}. Note=Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. Localizes to the inner kinetochore, and may connect it to the outer kinetochore via its N-terminus. {ECO:0000269|PubMed:19412974}. |
| Mouse PG classification | NA |
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