Gene Information
Gene NameTMEM116
OrganismHomo sapiens (Human)
Gene Length245
Protein NamesTransmembrane protein 116
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000198270 )
Evolutionary StageEumetazoa
AlphaFoldDBQ8NCL8
Gene CardTMEM116
Uniprot IDQ8NCL8
PfamNA
In ASDno
Allosteric Predictionno (-1.117034566)
Ortholog in AnimalsAlpaca_ TMEM116 ( ortholog_one2one )
Dog_ TMEM116 ( ortholog_one2one )
GuineaPig_ TMEM116 ( ortholog_one2one )
Macaque_ TMEM116 ( ortholog_one2one )
Mouse_ Tmem116 ( ortholog_one2one )
Pig_ TMEM116 ( ortholog_one2one )
Rat_ Tmem116 ( ortholog_one2one )
Rabbit_ TMEM116 ( ortholog_one2one )
OhnologsNA
ParalogsGPR157
Tissueheart, kidney, left.ventricle, pulmonary.valve
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3752630 
Subcellular location [CC]Membrane {ECO:0000305};
Multi-pass membrane protein {ECO:0000305}.
Mouse PG classificationNA
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