Gene Information
Gene NameICAM5
OrganismHomo sapiens (Human)
Gene Length924
Protein NamesIntercellular adhesion molecule 5 (ICAM-5) (Telencephalin)
Target NameNA
Target TypeNA
Gene Age168 ( ENSG00000105376 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9UMF0
Gene CardICAM5
Uniprot IDQ9UMF0
PfamPF03921
In ASDno
Allosteric Predictionno (-0.561424348)
Ortholog in AnimalsAlpaca_ ICAM5 ( ortholog_one2one )
Dog_ ICAM5 ( ortholog_one2one )
GuineaPig_ ICAM5 ( ortholog_one2one )
Macaque_ ICAM5 ( ortholog_one2one )
Mouse_ Icam5 ( ortholog_one2one )
Pig_ ICAM5 ( ortholog_one2one )
Rat_ Icam5 ( ortholog_one2one )
OhnologsNA
ParalogsICAM1, ICAM2, ICAM3, ICAM4
Tissuebrain, cerebral.cortex, caudate.nucleus, hippocampus, nucleus.accumbens, putamen
Tissue SpecificityExpressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.010990(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3BN3  (X-ray  2.10A  4OI9  (X-ray  2.50A  4OIA  (X-ray  3.70A  4OIB  (X-ray  3.50A 
DBSNP rs1056538  rs2228615 
Subcellular location [CC]Membrane;
Single-pass type I membrane protein.
Mouse PG classificationNA
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