| Gene Information | |
|---|---|
| Gene Name | IC53 |
| Organism | Homo sapiens (Human) |
| Gene Length | 506 |
| Protein Names | CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53) (LXXLL/leucine-zipper-containing ARF-binding protein) (Protein HSF-27) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96JB5 |
| Gene Card | CDK5RAP3 |
| Uniprot ID | Q96JB5 |
| Pfam | PF05600 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed (PubMed:12054757, PubMed:10721722). Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform 3 is expressed in kidney, liver, skeletal muscle and placenta (PubMed:12737517). {ECO:0000269|PubMed:10721722, ECO:0000269|PubMed:12054757, ECO:0000269|PubMed:12737517}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35054799 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16173922}. Cytoplasm {ECO:0000269|PubMed:15790566, ECO:0000269|PubMed:16173922, ECO:0000269|PubMed:19223857}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:19223857}. Note=Colocalizes and associates with microtubules. {ECO:0000269|PubMed:23478299}. |
| Mouse PG classification | NA |
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