| Gene Information | |
|---|---|
| Gene Name | CDH6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 790 |
| Protein Names | Cadherin-6 (Kidney cadherin) (K-cadherin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000113361 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P55285 |
| Gene Card | CDH6 |
| Uniprot ID | P55285 |
| Pfam | PF01049; PF00028 |
| In ASD | no |
| Allosteric Prediction | no (-0.637215689) |
| Ortholog in Animals | Alpaca_ CDH6 ( ortholog_one2one ) Dog_ CDH6 ( ortholog_one2one ) GuineaPig_ CDH6 ( ortholog_one2one ) Macaque_ CDH6 ( ortholog_one2one ) Mouse_ Cdh6 ( ortholog_one2one ) Pig_ CDH6 ( ortholog_one2one ) Rat_ Cdh6 ( ortholog_one2one ) Rabbit_ CDH6 ( ortholog_one2one ) |
| Ohnologs | CDH1, CDH3, CDH15, CDH24, CDH11, CDH13, CDH22, CDH8, CDH5 |
| Paralogs | CDH7, CDH9, CDH20, CDH4, CDH18, PCDH1, PCDH20, CDH26, CDH19, PCDH9, CDH3, PCDH11Y, PCDH11X, CDH17, CDHR5, CDHR3, DCHS2, CDH24, CDH23, PCDH7, CDH15, CDHR1, DCHS1, CDH11, CDH8, CDH10, CDH12, CDH13, CDH1, CDHR2, CDH22, CDH5, CDH2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5VEB (X-ray 2.34A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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