| Gene Information | |
|---|---|
| Gene Name | P2RY2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 377 |
| Protein Names | P2Y purinoceptor 2 (P2Y2) (ATP receptor) (P2U purinoceptor 1) (P2U1) (P2U receptor 1) (Purinergic receptor) |
| Target Name | p2y purinoceptor 2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000175591 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P41231 |
| Gene Card | P2RY2 |
| Uniprot ID | P41231 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.275875207) |
| Ortholog in Animals | Alpaca_ P2RY2 ( ortholog_one2one ) Dog_ P2RY2 ( ortholog_one2one ) GuineaPig_ P2RY2 ( ortholog_one2one ) Macaque_ P2RY2 ( ortholog_one2one ) Mouse_ P2ry2 ( ortholog_one2one ) Pig_ P2RY2 ( ortholog_one2one ) Rat_ P2ry2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FFAR3, GPR42, FFAR2, GPR82, GPR31, FFAR1, HCAR3, HCAR1, HCAR2, OXER1, P2RY4, P2RY6, P2RY1, OXGR1, SUCNR1 |
| Tissue | esophagus.mucosa, skeletal.muscle, vagina |
| Tissue Specificity | Spleen, testis, kidney, liver, lung, heart and brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2511241 rs3741156 rs1626154 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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