| Gene Information | |
|---|---|
| Gene Name | LEMD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 181 |
| Protein Names | LEM domain-containing protein 1 (Cancer/testis antigen 50) (CT50) (LEM domain protein 1) (LEMP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000186007 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q68G75 |
| Gene Card | LEMD1 |
| Uniprot ID | Q68G75 |
| Pfam | PF03020 |
| In ASD | no |
| Allosteric Prediction | no (-1.913666881) |
| Ortholog in Animals | Alpaca_ LEMD1 ( ortholog_one2one ) Dog_ LEMD1 ( ortholog_one2one ) Macaque_ LEMD1 ( ortholog_one2one ) Mouse_ Lemd1 ( ortholog_one2one ) Pig_ LEMD1 ( ortholog_one2one ) Rat_ Lemd1 ( ortholog_one2one ) Rabbit_ LEMD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TMPO |
| Tissue | testis |
| Tissue Specificity | Testis-specific. Isoform 6 is detected in 17 of 18 colon cancer tissues examined. {ECO:0000269|PubMed:15254688}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7531012 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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