| Gene Information | |
|---|---|
| Gene Name | IARS |
| Organism | Homo sapiens (Human) |
| Gene Length | 1262 |
| Protein Names | Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS) |
| Target Name | isoleucine--trna ligase, cytoplasmic |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P41252 |
| Gene Card | IARS1 |
| Uniprot ID | P41252 |
| Pfam | PF08264; PF00133 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in liver and muscle (at protein level). {ECO:0000269|PubMed:27426735}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.064059(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs140666586 rs886037876 rs886037874 rs2070053 rs886037877 rs886037873 rs556155 rs201071417 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:27426735, ECO:0000269|PubMed:7721108}. Cytoplasm, cytosol {ECO:0000269|PubMed:19289464}. |
| Mouse PG classification | NA |
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