| Gene Information | |
|---|---|
| Gene Name | HYPE |
| Organism | Homo sapiens (Human) |
| Gene Length | 458 |
| Protein Names | Protein adenylyltransferase FICD (EC 2.7.7.108) (AMPylator FICD) (De-AMPylase FICD) (EC 3.1.4.-) (FIC domain-containing protein) (Huntingtin yeast partner E) (Huntingtin-interacting protein 13) (HIP-13) (Huntingtin-interacting protein E) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BVA6 |
| Gene Card | FICD |
| Uniprot ID | Q9BVA6 |
| Pfam | PF02661 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:19362538}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4U04 (X-ray 2.48A ) 4U07 (X-ray 2.64A ) 4U0S (X-ray 2.49A ) 4U0U (X-ray 2.98A ) 4U0Z (X-ray 2.95A ) 6I7G (X-ray 2.70A ) 6I7H (X-ray 2.25A ) 6I7I (X-ray 2.33A ) 6I7J (X-ray 2.65A ) 6I7K (X-ray 2.54A ) 6I7L (X-ray 2.32A ) 6ZMD (X-ray 2.64A ) 7B7Z (X-ray 1.70A ) 7B80 (X-ray 1.87A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:25601083}; Single-pass type II membrane protein {ECO:0000305|PubMed:25601083}. |
| Mouse PG classification | NA |
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