| Gene Information | |
|---|---|
| Gene Name | KDM4B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1096 |
| Protein Names | Lysine-specific demethylase 4B (EC 1.14.11.66) (JmjC domain-containing histone demethylation protein 3B) (Jumonji domain-containing protein 2B) ([histone H3]-trimethyl-L-lysine(9) demethylase 4B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000127663 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O94953 |
| Gene Card | KDM4B |
| Uniprot ID | O94953 |
| Pfam | PF02373; PF02375; PF18104 |
| In ASD | no |
| Allosteric Prediction | yes (0.571024594) |
| Ortholog in Animals | Alpaca_ KDM4B ( ortholog_one2one ) Dog_ KDM4B ( ortholog_one2one ) GuineaPig_ KDM4B ( ortholog_one2one ) Macaque_ KDM4B ( ortholog_one2one ) Mouse_ Kdm4b ( ortholog_one2one ) Pig_ KDM4B ( ortholog_one2one ) Rat_ Kdm4b ( ortholog_one2one ) |
| Ohnologs | KDM4A, KDM4C, KDM4D |
| Paralogs | JARID2, KDM4C, KDM4F, KDM4E, KDM4D, KDM5B, KDM5C, KDM5D, KDM4A, KDM5A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4LXL (X-ray 1.87A ) 4UC4 (X-ray 2.56A ) 7JM5 (X-ray 2.70A ) |
| DBSNP | rs11667206 rs2620836 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537, ECO:0000269|PubMed:15927959}. |
| Mouse PG classification | NA |
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