Gene Information
Gene NameHY
OrganismHomo sapiens (Human)
Gene Length1539
Protein NamesLysine-specific demethylase 5D (EC 1.14.11.67) (Histocompatibility Y antigen) (H-Y) (Histone demethylase JARID1D) (Jumonji/ARID domain-containing protein 1D) (Protein SmcY) ([histone H3]-trimethyl-L-lysine(4) demethylase 5D)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9BY66
Gene CardKDM5D
Uniprot IDQ9BY66
PfamPF01388; PF02373; PF02375; PF00628; PF08429; PF02928
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpression is highly down-regulated in metastatic prostate tumors. {ECO:0000269|PubMed:26747897}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2E6R  (NMR  2YQE  (NMR 
DBSNP rs1050807 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:27185910, ECO:0000269|PubMed:27477906, ECO:0000305}.
Mouse PG classificationNA
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