Gene Information | |
---|---|
Gene Name | HTR7 |
Organism | Homo sapiens (Human) |
Gene Length | 479 |
Protein Names | 5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7) |
Target Name | 5-hydroxytryptamine receptor 7 |
Target Type | NA |
Gene Age | 645 ( ENSG00000148680 ) |
Evolutionary Stage | Eumetazoa |
AlphaFoldDB | P34969 |
Gene Card | HTR7 |
Uniprot ID | P34969 |
Pfam | PF00001 |
In ASD | yes |
Allosteric Prediction | yes (1.472154699) |
Ortholog in Animals | Alpaca_ HTR7 ( ortholog_one2one ) Dog_ HTR7 ( ortholog_one2one ) GuineaPig_ HTR7 ( ortholog_one2one ) Macaque_ HTR7 ( ortholog_one2one ) Mouse_ Htr7 ( ortholog_one2one ) Pig_ HTR7 ( ortholog_one2one ) Rat_ Htr7 ( ortholog_one2one ) Rabbit_ HTR7 ( ortholog_one2one ) |
Ohnologs | ADRA1D, ADRA1A, HTR1B, HTR5A, HTR4, ADRA1B |
Paralogs | HTR6, HTR5A, HTR1E, HTR1B, HTR1F, HTR2C, HTR2A, HTR2B |
Tissue | testis |
Tissue Specificity | Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in terms of expression. {ECO:0000269|PubMed:9084407}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
|
Gene Ontology (cellular component) |
|
Gene Ontology (molecular function) |
|
PDB | 7XTC (EM 3.20A ) |
DBSNP | rs1379762209 rs114969659 rs33954285 |
Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
Mouse PG classification | NA |
click here to return to the previous page |