| Gene Information | |
|---|---|
| Gene Name | CARD19 |
| Organism | Homo sapiens (Human) |
| Gene Length | 228 |
| Protein Names | Caspase recruitment domain-containing protein 19 (Bcl10-interacting CARD protein) (BinCARD) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000165233 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96LW7 |
| Gene Card | CARD19 |
| Uniprot ID | Q96LW7 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.476356556) |
| Ortholog in Animals | Alpaca_ CARD19 ( ortholog_one2one ) Dog_ CARD19 ( ortholog_one2one ) GuineaPig_ CARD19 ( ortholog_one2one ) Macaque_ CARD19 ( ortholog_one2one ) Mouse_ Card19 ( ortholog_one2one ) Pig_ CARD19 ( ortholog_one2one ) Rat_ Card19 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain. {ECO:0000269|PubMed:15637807}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4DWN (X-ray 1.58A ) 4FH0 (X-ray 1.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Nucleus {ECO:0000269|PubMed:23633586}. Note=Coexpression with BCL10 induced translocation from nucleus to cytosol.; [Isoform 2]: Endoplasmic reticulum membrane {ECO:0000269|PubMed:23633586}; Single-pass membrane protein {ECO:0000269|PubMed:23633586}. Mitochondrion membrane {ECO:0000269|PubMed:23633586}; Single-pass membrane protein {ECO:0000269|PubMed:23633586}. |
| Mouse PG classification | NA |
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