| Gene Information | |
|---|---|
| Gene Name | TNPO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 898 |
| Protein Names | Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000083312 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92973 |
| Gene Card | TNPO1 |
| Uniprot ID | Q92973 |
| Pfam | PF03810 |
| In ASD | no |
| Allosteric Prediction | yes (0.233529275) |
| Ortholog in Animals | Alpaca_ TNPO1 ( ortholog_one2one ) Dog_ TNPO1 ( ortholog_one2one ) GuineaPig_ TNPO1 ( ortholog_one2one ) Macaque_ TNPO1 ( ortholog_one2one ) Mouse_ Tnpo1 ( ortholog_one2one ) Pig_ TNPO1 ( ortholog_one2one ) Rat_ Tnpo1 ( ortholog_one2one ) Rabbit_ TNPO1 ( ortholog_one2one ) |
| Ohnologs | TNPO2 |
| Paralogs | IPO5, TNPO2, RANBP6, KPNB1, IPO4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001628(Rat);0.023529(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1QBK (X-ray 3.00A ) 2H4M (X-ray 3.05A ) 2OT8 (X-ray 3.10A ) 2QMR (X-ray 3.00A ) 2Z5J (X-ray 3.40A ) 2Z5K (X-ray 2.60A ) 2Z5M (X-ray 3.00A ) 2Z5N (X-ray 3.20A ) 2Z5O (X-ray 3.20A ) 4FDD (X-ray 2.30A ) 4FQ3 (X-ray 3.00A ) 4JLQ (X-ray 3.05A ) 4OO6 (X-ray 2.70A ) 5J3V (X-ray 3.05A ) 5TQC (X-ray 3.00A ) 5YVG (X-ray 4.05A ) 5YVH (X-ray 3.15A ) 5YVI (X-ray 2.90A ) 7CYL (X-ray 2.70A ) 7VPW (X-ray 3.76A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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