| Gene Information | |
|---|---|
| Gene Name | RHOD |
| Organism | Homo sapiens (Human) |
| Gene Length | 210 |
| Protein Names | Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000173156 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O00212 |
| Gene Card | RHOD |
| Uniprot ID | O00212 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.572298539) |
| Ortholog in Animals | Alpaca_ RHOD ( ortholog_one2one ) Dog_ RHOD ( ortholog_one2one ) GuineaPig_ RHOD ( ortholog_one2one ) Macaque_ RHOD ( ortholog_one2one ) Mouse_ Rhod ( ortholog_one2one ) Pig_ RHOD ( ortholog_one2one ) Rat_ Rhod ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RND1, CDC42, RHOT1, RHOBTB3, RHOT2, RAC1, RAC3, RHOJ, RHOA, RHOC, RHOB, RHOV, RHOQ, RHOBTB2, RND2, RND3, RHOF, RHOG, RHOU, RAC2, RHOBTB1, RHOH |
| Tissue | NA |
| Tissue Specificity | Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2J1L (X-ray 2.50A ) 7KDC (X-ray 3.10A ) |
| DBSNP | rs4930409 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Early endosome {ECO:0000269|PubMed:24102721}. Note=Colocalizes with RAB5 to early endosomes (By similarity). {ECO:0000250|UniProtKB:P97348}. |
| Mouse PG classification | NA |
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