| Gene Information | |
|---|---|
| Gene Name | HLX |
| Organism | Homo sapiens (Human) |
| Gene Length | 488 |
| Protein Names | H2.0-like homeobox protein (Homeobox protein HB24) (Homeobox protein HLX1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000136630 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14774 |
| Gene Card | HLX |
| Uniprot ID | Q14774 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | no (-0.922118405) |
| Ortholog in Animals | Alpaca_ HLX ( ortholog_one2one ) Dog_ HLX ( ortholog_one2one ) GuineaPig_ HLX ( ortholog_one2one ) Macaque_ HLX ( ortholog_one2one ) Mouse_ Hlx ( ortholog_one2one ) Pig_ HLX ( ortholog_one2one ) Rat_ Hlx ( ortholog_one2one ) Rabbit_ HLX ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LEUTX, DBX2, DBX1 |
| Tissue | bone.marrow |
| Tissue Specificity | Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12141189 rs2738755 rs11578466 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
| Mouse PG classification | NA |
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