| Gene Information | |
|---|---|
| Gene Name | DFFA |
| Organism | Homo sapiens (Human) |
| Gene Length | 331 |
| Protein Names | DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000160049 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O00273 |
| Gene Card | DFFA |
| Uniprot ID | O00273 |
| Pfam | PF02017; PF09033 |
| In ASD | no |
| Allosteric Prediction | yes (0.08967333) |
| Ortholog in Animals | Alpaca_ DFFA ( ortholog_one2one ) Dog_ DFFA ( ortholog_one2one ) GuineaPig_ DFFA ( ortholog_one2one ) Macaque_ DFFA ( ortholog_one2one ) Mouse_ Dffa ( ortholog_one2one ) Pig_ DFFA ( ortholog_one2one ) Rat_ Dffa ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CIDEC, CIDEB, CIDEA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1IBX (NMR - ) 1IYR (NMR - ) 1KOY (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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