| Gene Information | |
|---|---|
| Gene Name | NAT8L |
| Organism | Homo sapiens (Human) |
| Gene Length | 302 |
| Protein Names | N-acetylaspartate synthetase (NAA synthetase) (EC 2.3.1.17) (Camello-like protein 3) (N-acetyltransferase 8-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000185818 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N9F0 |
| Gene Card | NAT8L |
| Uniprot ID | Q8N9F0 |
| Pfam | PF00583 |
| In ASD | no |
| Allosteric Prediction | no (-0.745119054) |
| Ortholog in Animals | Alpaca_ NAT8L ( ortholog_one2one ) Dog_ NAT8L ( ortholog_one2one ) Mouse_ Nat8l ( ortholog_one2one ) Pig_ NAT8L ( ortholog_one2one ) Rat_ Nat8l ( ortholog_one2one ) |
| Ohnologs | NAT8 |
| Paralogs | NAT8, NAT14, NAT8B |
| Tissue | adipose.tissue, brain, cerebral.cortex, occipital.lobe |
| Tissue Specificity | Expressed in brain. {ECO:0000269|PubMed:19807691}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19524112}. Microsome membrane {ECO:0000250|UniProtKB:D3ZVU9}; Single-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:19524112}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q3UGX3}; Single-pass membrane protein {ECO:0000255}. Note=Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment. {ECO:0000269|PubMed:19524112}. |
| Mouse PG classification | LPG |
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