| Gene Information | |
|---|---|
| Gene Name | HOOK3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 718 |
| Protein Names | Protein Hook homolog 3 (h-hook3) (hHK3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000168172 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86VS8 |
| Gene Card | HOOK3 |
| Uniprot ID | Q86VS8 |
| Pfam | PF05622; PF19047 |
| In ASD | no |
| Allosteric Prediction | no (-1.430399624) |
| Ortholog in Animals | Alpaca_ HOOK3 ( ortholog_one2one ) Dog_ FNTA ( ortholog_one2one ) GuineaPig_ HOOK3 ( ortholog_one2one ) Macaque_ HOOK3 ( ortholog_one2one ) Mouse_ Hook3 ( ortholog_one2one ) Pig_ HOOK3 ( ortholog_one2one ) Rat_ AABR07026291.1 ( ortholog_one2one ) Rabbit_ HOOK3 ( ortholog_one2one ) |
| Ohnologs | HOOK1 |
| Paralogs | HOOK1, CCDC88A, CCDC88B, CCDC88C, HOOK2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5J8E (X-ray 1.70A ) 6B9H (X-ray 1.50A ) |
| DBSNP | rs34131505 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11238449}. Golgi apparatus {ECO:0000269|PubMed:11238449}. Note=Enriched at the cis-face of the Golgi complex. Localizes to microtubule asters in prophase (PubMed:11238449). Localizes to the manchette in elongating spermatids (By similarity). {ECO:0000250|UniProtKB:Q8BUK6, ECO:0000269|PubMed:11238449}. |
| Mouse PG classification | NA |
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