| Gene Information | |
|---|---|
| Gene Name | HTD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 168 |
| Protein Names | Hydroxyacyl-thioester dehydratase type 2, mitochondrial (HsHTD2) (EC 4.2.1.59) (3-hydroxyacyl-[acyl-carrier-protein] dehydratase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000255154 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P86397 |
| Gene Card | HTD2 |
| Uniprot ID | P86397 |
| Pfam | PF01575 |
| In ASD | no |
| Allosteric Prediction | no (-1.360218962) |
| Ortholog in Animals | Alpaca_ HTD2 ( ortholog_one2one ) Dog_ HTD2 ( ortholog_one2one ) GuineaPig_ HTD2 ( ortholog_one2one ) Macaque_ HTD2 ( ortholog_one2one ) Mouse_ Rpp14 ( ortholog_one2one ) Pig_ HTD2 ( ortholog_one2one ) Rat_ Rpp14 ( ortholog_one2one ) Rabbit_ HTD2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart and liver. Expressed at lower levels in skeletal muscle, spleen, kidney and placenta. {ECO:0000269|PubMed:17898086}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3IR3 (X-ray 1.99A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:17898086}. |
| Mouse PG classification | NA |
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