| Gene Information | |
|---|---|
| Gene Name | HELZ2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2649 |
| Protein Names | Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000130589 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BYK8 |
| Gene Card | HELZ2 |
| Uniprot ID | Q9BYK8 |
| Pfam | PF13086; PF13087; PF00773 |
| In ASD | no |
| Allosteric Prediction | no (-0.236135616) |
| Ortholog in Animals | Alpaca_ HELZ2 ( ortholog_one2one ) GuineaPig_ HELZ2 ( ortholog_one2one ) Macaque_ HELZ2 ( ortholog_one2one ) Mouse_ Helz2 ( ortholog_one2one ) Pig_ HELZ2 ( ortholog_one2one ) Rat_ Helz2 ( ortholog_one2one ) |
| Ohnologs | HELZ |
| Paralogs | SETX, AQR, UPF1, DNA2, IGHMBP2, HELZ, ZNFX1, MOV10, MOV10L1, CT55 |
| Tissue | NA |
| Tissue Specificity | Expressed in various tissues including heart, pancreas, skeletal muscle, colon, spleen, liver, kidney, lung, peripheral blood and placenta. {ECO:0000269|PubMed:16239304}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001823(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs438363 rs310632 rs35817585 rs310631 rs3810487 rs3810486 rs34980032 rs3810485 rs3810483 rs3810481 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:23525231}. |
| Mouse PG classification | NA |
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