| Gene Information | |
|---|---|
| Gene Name | IFITM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 132 |
| Protein Names | Interferon-induced transmembrane protein 2 (Dispanin subfamily A member 2c) (DSPA2c) (Interferon-inducible protein 1-8D) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000185201 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q01629 |
| Gene Card | IFITM2 |
| Uniprot ID | Q01629 |
| Pfam | PF04505 |
| In ASD | no |
| Allosteric Prediction | no (-1.577110403) |
| Ortholog in Animals | Alpaca_ IFITM2 ( ortholog_one2one ) Macaque_ IFITM2 ( ortholog_one2one ) Mouse_ Ifitm3 ( ortholog_many2many ) Mouse_ Ifitm2 ( ortholog_many2many ) Mouse_ Ifitm1 ( ortholog_many2many ) Mouse_ Ifitm7 ( ortholog_many2many ) Rat_ AABR07015596.1 ( ortholog_many2many ) Rat_ Ifitm1 ( ortholog_many2many ) Rat_ Ifitm3 ( ortholog_many2many ) Rat_ AABR07021463.1 ( ortholog_many2many ) Rat_ Ifitm2 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | IFITM1, IFITM3, IFITM5, IFITM10 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1058900 rs14408 rs1059091 |
| Subcellular location [CC] | Cell membrane {ECO:0000305|PubMed:33563656}; Single-pass type II membrane protein {ECO:0000305}. Lysosome membrane {ECO:0000269|PubMed:26354436}; Single-pass type II membrane protein {ECO:0000305}. Late endosome membrane {ECO:0000269|PubMed:26354436}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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