| Gene Information | |
|---|---|
| Gene Name | APOL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 337 |
| Protein Names | Apolipoprotein L2 (Apolipoprotein L-II) (ApoL-II) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000128335 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9BQE5 |
| Gene Card | APOL2 |
| Uniprot ID | Q9BQE5 |
| Pfam | PF05461 |
| In ASD | no |
| Allosteric Prediction | no (-0.999779829) |
| Ortholog in Animals | Alpaca_ APOL2 ( ortholog_one2one ) Macaque_ APOL2 ( ortholog_one2one ) Mouse_ Apol7a ( ortholog_many2many ) Mouse_ Apol7c ( ortholog_many2many ) Mouse_ Apol11a ( ortholog_many2many ) Mouse_ Apol8 ( ortholog_many2many ) Mouse_ Apol7e ( ortholog_many2many ) Mouse_ Apol7b ( ortholog_many2many ) Mouse_ Apol11b ( ortholog_many2many ) Mouse_ Apol10a ( ortholog_many2many ) Mouse_ Apol9a ( ortholog_many2many ) Mouse_ Apol9b ( ortholog_many2many ) Mouse_ Apol10b ( ortholog_many2many ) Rat_ Apol3 ( ortholog_many2many ) Rat_ AABR07058464.1 ( ortholog_many2many ) Rat_ AABR07058479.1 ( ortholog_many2many ) Rat_ Apol2 ( ortholog_many2many ) Rat_ RGD1309808 ( ortholog_many2many ) Rat_ Apol9a ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | APOL1, APOL3, APOL4, APOL6, APOL5, APOLD1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed; the highest levels are found in lung, thymus, pancreas, placenta, adult brain and prostate; also detected in spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea, mammary gland, skeletal muscle, testis and fetal brain and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7LF8 (X-ray 2.15A ) |
| DBSNP | rs7285167 rs132760 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |