| Gene Information | |
|---|---|
| Gene Name | AGFG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 562 |
| Protein Names | Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein) (Nucleoporin-like protein RIP) (Rev-interacting protein) (Rev/Rex activation domain-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000173744 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P52594 |
| Gene Card | AGFG1 |
| Uniprot ID | P52594 |
| Pfam | PF01412 |
| In ASD | no |
| Allosteric Prediction | no (-0.500566333) |
| Ortholog in Animals | Alpaca_ AGFG1 ( ortholog_one2one ) Dog_ AGFG1 ( ortholog_one2one ) GuineaPig_ AGFG1 ( ortholog_one2one ) Macaque_ AGFG1 ( ortholog_one2one ) Mouse_ Agfg1 ( ortholog_one2one ) Pig_ AGFG1 ( ortholog_one2one ) Rat_ AABR07054262.1 ( ortholog_one2one ) Rabbit_ AGFG1 ( ortholog_one2one ) |
| Ohnologs | AGFG2 |
| Paralogs | ASAP2, ASAP1, ACAP3, ARAP2, GIT1, ARAP3, ADAP1, SMAP1, AGAP1, ACAP2, AGAP3, AGAP4, AGAP6, AGAP9, AGAP5, ARFGAP1, ASAP3, APPL1, ARFGAP2, ARAP1, AGFG2, APPL2, ARFGAP3, GIT2, ADAP2, SMAP2, AGAP2, ACAP1 |
| Tissue | testis |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:7634337}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2D9L (NMR - ) 2OLM (X-ray 1.48A ) 2VX8 (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10613896, ECO:0000269|PubMed:7634337}. Cytoplasmic vesicle {ECO:0000269|PubMed:10613896}. |
| Mouse PG classification | NA |
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