| Gene Information | |
|---|---|
| Gene Name | HSPH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 858 |
| Protein Names | Heat shock protein 105 kDa (Antigen NY-CO-25) (Heat shock 110 kDa protein) |
| Target Name | heat shock protein 105 kda |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000120694 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q92598 |
| Gene Card | HSPH1 |
| Uniprot ID | Q92598 |
| Pfam | PF00012 |
| In ASD | no |
| Allosteric Prediction | yes (0.594501517) |
| Ortholog in Animals | Alpaca_ HSPH1 ( ortholog_one2one ) Dog_ HSPH1 ( ortholog_one2one ) Macaque_ HSPH1 ( ortholog_one2one ) Mouse_ Hsph1 ( ortholog_one2one ) Pig_ HSPH1 ( ortholog_one2one ) Rat_ Hsph1 ( ortholog_one2one ) Rabbit_ HSPH1 ( ortholog_one2one ) |
| Ohnologs | HSPA4L, HSPA4 |
| Paralogs | HSPA4L, HSPA6, HSPA1L, HSPA2, HSPA1A, HSPA1B, HSPA9, HSPA13, HSPA5, HSPA14, HSPA8, HYOU1, HSPA4 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. {ECO:0000269|PubMed:10865058, ECO:0000269|PubMed:16232202}. |
| Pharmacological Animal Models | 0.080916(Chimpanzee);0.046358(Mouse);0.001335(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 6GFA (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9931472}. |
| Mouse PG classification | NA |
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