Gene Information
Gene NameHSPC275
OrganismHomo sapiens (Human)
Gene Length1220
Protein NamesProtein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO94979
Gene CardSEC31A
Uniprot IDO94979
PfamPF12931
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityAbundantly and ubiquitously expressed. {ECO:0000269|PubMed:10574704, ECO:0000269|PubMed:10788476}.
Pharmacological Animal ModelsNULL(Chimpanzee);0.036082(Mouse);0.095305(Rat);0.061488(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3WXA  (X-ray  2.36A  7SUL  (X-ray  2.40A 
DBSNP rs34554214  rs3797036  rs35579207  rs35739017 
Subcellular location [CC]Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000269|PubMed:10788476, ECO:0000269|PubMed:16957052, ECO:0000269|PubMed:22358839, ECO:0000269|PubMed:27716508};
Peripheral membrane protein;
Cytoplasmic side. Endoplasmic reticulum membrane {ECO:0000250};
Peripheral membrane protein {ECO:0000250}. Cytoplasm, cytosol {ECO:0000269|PubMed:17428803}. Note=Associates with membranes in a GTP-dependent manner (By similarity). Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:25201882, PubMed:28442536, PubMed:17428803). {ECO:0000250|UniProtKB:Q9Z2Q1, ECO:0000269|PubMed:17428803, ECO:0000269|PubMed:25201882, ECO:0000269|PubMed:28442536}.
Mouse PG classificationNA
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