| Gene Information | |
|---|---|
| Gene Name | METTL5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 209 |
| Protein Names | rRNA N6-adenosine-methyltransferase METTL5 (EC 2.1.1.-) (Methyltransferase-like protein 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000138382 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9NRN9 |
| Gene Card | METTL5 |
| Uniprot ID | Q9NRN9 |
| Pfam | PF05175 |
| In ASD | no |
| Allosteric Prediction | no (-1.875391971) |
| Ortholog in Animals | Alpaca_ METTL5 ( ortholog_one2one ) Dog_ METTL5 ( ortholog_one2one ) GuineaPig_ METTL5 ( ortholog_one2one ) Macaque_ METTL5 ( ortholog_one2one ) Mouse_ Mettl5 ( ortholog_one2one ) Pig_ METTL5 ( ortholog_one2one ) Rat_ Mettl5 ( ortholog_one2one ) Rabbit_ METTL5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed from very early development (8 post-conceptual weeks) and expression persists through adulthood in multiple substructures of the brain, including the cerebellar cortex, hippocampus, and striatum. {ECO:0000269|PubMed:31564433}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6H2U (X-ray 1.60A ) 6H2V (X-ray 2.49A ) |
| DBSNP | rs1051387 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:31564433}. Presynapse {ECO:0000269|PubMed:31564433}. Postsynapse {ECO:0000269|PubMed:31564433}. |
| Mouse PG classification | NA |
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