| Gene Information | |
|---|---|
| Gene Name | PGRMC |
| Organism | Homo sapiens (Human) |
| Gene Length | 195 |
| Protein Names | Membrane-associated progesterone receptor component 1 (mPR) (Dap1) (IZA) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O00264 |
| Gene Card | PGRMC1 |
| Uniprot ID | O00264 |
| Pfam | PF00173 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest expression in liver and kidney. Expressed by endometrial glands and stroma (at protein level) (PubMed:23793472). {ECO:0000269|PubMed:23793472}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4X8Y (X-ray 1.95A ) |
| DBSNP | NA |
| Subcellular location [CC] | Microsome membrane {ECO:0000250|UniProtKB:Q95250}; Single-pass membrane protein {ECO:0000255}. Smooth endoplasmic reticulum membrane {ECO:0000303|PubMed:28396637}; Single-pass membrane protein {ECO:0000255}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:O55022}; Single-pass membrane protein {ECO:0000305}; Extracellular side {ECO:0000250|UniProtKB:O55022}. |
| Mouse PG classification | NA |
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