Gene Information
Gene NameHSPC184
OrganismHomo sapiens (Human)
Gene Length183
Protein NamesER membrane protein complex subunit 4 (Cell proliferation-inducing gene 17 protein) (Transmembrane protein 85)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ5J8M3
Gene CardEMC4
Uniprot IDQ5J8M3
PfamPF06417
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityIsoform 1 is expressed in brain and heart. Isoform 2 is expressed in heart. {ECO:0000269|PubMed:18586032}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.020410(Rat);0.049150(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6Z3W  (EM  6.40A  7ADO  (EM  3.39A  7ADP  (EM  3.60A 
DBSNP rs11544437 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000269|PubMed:22119785};
Multi-pass membrane protein {ECO:0000305|PubMed:32439656, ECO:0000305|PubMed:32459176}. Note=Could also be a single-pass transmembrane protein with cytosolic N-terminus and lumenal C-terminus. {ECO:0000305|PubMed:32439656, ECO:0000305|PubMed:32459176}.
Mouse PG classificationNA
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