Gene Information
Gene NameTHAP4
OrganismHomo sapiens (Human)
Gene Length577
Protein NamesPeroxynitrite isomerase THAP4 (EC 5.99.-.-) (Ferric Homo sapiens nitrobindin) (Hs-Nb(III)) (THAP domain-containing protein 4)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000176946 )
Evolutionary StageEukaryota
AlphaFoldDBQ8WY91
Gene CardTHAP4
Uniprot IDQ8WY91
PfamPF05485; PF08768
In ASDno
Allosteric Predictionno (-0.995511525)
Ortholog in AnimalsAlpaca_ THAP4 ( ortholog_one2one )
Dog_ THAP4 ( ortholog_one2one )
GuineaPig_ THAP4 ( ortholog_one2one )
Macaque_ THAP4 ( ortholog_one2one )
Mouse_ Thap4 ( ortholog_one2one )
Pig_ THAP4 ( ortholog_one2one )
Rat_ Thap4 ( ortholog_one2one )
Rabbit_ THAP4 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3IA8  (X-ray  1.79A 
DBSNP rs7424328 
Subcellular location [CC]Cytoplasm. Nucleus. Note=Localizes mainly in the cytoplasm and partially in the nucleus. {ECO:0000269|PubMed:32295384}.
Mouse PG classificationNA
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