| Gene Information | |
|---|---|
| Gene Name | CEP85L |
| Organism | Homo sapiens (Human) |
| Gene Length | 805 |
| Protein Names | Centrosomal protein of 85 kDa-like (Serologically defined breast cancer antigen NY-BR-15) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000111860 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5SZL2 |
| Gene Card | CEP85L |
| Uniprot ID | Q5SZL2 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.11947469) |
| Ortholog in Animals | Alpaca_ CEP85L ( ortholog_one2one ) Dog_ CEP85L ( ortholog_one2one ) GuineaPig_ CEP85L ( ortholog_one2one ) Macaque_ CEP85L ( ortholog_one2one ) Mouse_ Cep85l ( ortholog_one2one ) Pig_ CEP85L ( ortholog_one2one ) Rat_ Cep85l ( ortholog_one2one ) Rabbit_ CEP85L ( ortholog_one2one ) |
| Ohnologs | CEP85 |
| Paralogs | CEP85 |
| Tissue | NA |
| Tissue Specificity | Isoform 1 and isoform 4 are expressed in spleen, lymph, thymus, tonsil and peripheral blood leukocytes, with isoform 1 expressed at higher levels. Isoform 4 is detected in K-562 leukemia cells and in the blood of precursor T lymphoblastic lymphoma (T-ALL) patients. {ECO:0000269|PubMed:21938754}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs3734381 rs9489444 rs3734382 rs9489410 rs7743702 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:21399614, ECO:0000269|PubMed:32097630}. Note=Localized specifically to the pericentriolar region. {ECO:0000269|PubMed:32097630}. |
| Mouse PG classification | NA |
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