| Gene Information | |
|---|---|
| Gene Name | IL17RC |
| Organism | Homo sapiens (Human) |
| Gene Length | 791 |
| Protein Names | Interleukin-17 receptor C (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor homolog) (IL17Rhom) (Interleukin-17 receptor-like protein) (IL-17RL) (ZcytoR14) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000163702 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8NAC3 |
| Gene Card | IL17RC |
| Uniprot ID | Q8NAC3 |
| Pfam | PF15037; PF08357 |
| In ASD | no |
| Allosteric Prediction | no (-1.007221842) |
| Ortholog in Animals | Alpaca_ IL17RC ( ortholog_one2one ) Dog_ IL17RC ( ortholog_one2one ) GuineaPig_ IL17RC ( ortholog_one2one ) Macaque_ IL17RC ( ortholog_one2one ) Mouse_ Il17rc ( ortholog_one2one ) Rat_ Il17rc ( ortholog_one2one ) Rabbit_ IL17RC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IL17RB, IL17RA, IL17RE, IL17RD |
| Tissue | NA |
| Tissue Specificity | Expressed in prostate, skeletal muscle, kidney and placenta (at protein level) (PubMed:11706037). Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate (PubMed:11706037). Also detected in thyroid, trachea and adrenal gland (PubMed:17911633). Low expression in thymus and leukocytes (PubMed:11706037). {ECO:0000269|PubMed:11706037, ECO:0000269|PubMed:17911633}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6HG4 (X-ray 3.32A ) 6HG9 (X-ray 3.62A ) 6HGA (X-ray 2.60A ) 7UWN (EM 3.01A ) |
| DBSNP | rs708567 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17911633}; Single-pass type I membrane protein {ECO:0000255}. Note=Soluble isoforms may be produced. |
| Mouse PG classification | NA |
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