| Gene Information | |
|---|---|
| Gene Name | HORMAD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 307 |
| Protein Names | HORMA domain-containing protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000176635 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N7B1 |
| Gene Card | HORMAD2 |
| Uniprot ID | Q8N7B1 |
| Pfam | PF02301 |
| In ASD | no |
| Allosteric Prediction | no (-0.745164504) |
| Ortholog in Animals | Alpaca_ HORMAD2 ( ortholog_one2one ) Dog_ HORMAD2 ( ortholog_one2one ) GuineaPig_ HORMAD2 ( ortholog_one2one ) Macaque_ HORMAD2 ( ortholog_one2one ) Mouse_ Hormad2 ( ortholog_one2one ) Pig_ HORMAD2 ( ortholog_one2one ) Rat_ Hormad2 ( ortholog_one2one ) Rabbit_ HORMAD2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HORMAD1 |
| Tissue | testis |
| Tissue Specificity | Highly expressed in testis (at protein level). Expressed in lung adenocarcinoma and squamous cell carcinoma (at protein level). Expressed at lower levels in the liver, brain and kidney. {ECO:0000269|PubMed:15999985, ECO:0000269|PubMed:22893617}. |
| Pharmacological Animal Models | 0.100380(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34150968 rs34305723 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:22893617}. Chromosome {ECO:0000250}. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the male and female prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |