Gene Information
Gene NamePRSS36
OrganismHomo sapiens (Human)
Gene Length855
Protein NamesPolyserase-2 (EC 3.4.21.-) (Polyserine protease 2) (Serine protease 36)
Target NameNA
Target TypeNA
Gene Age244 ( ENSG00000178226 )
Evolutionary StageEumetazoa
AlphaFoldDBQ5K4E3
Gene CardPRSS36
Uniprot IDQ5K4E3
PfamPF00089
In ASDno
Allosteric Predictionno (-0.917993764)
Ortholog in AnimalsAlpaca_ PRSS36 ( ortholog_one2one )
Dog_ PRSS36 ( ortholog_one2one )
GuineaPig_ PRSS36 ( ortholog_one2one )
Macaque_ PRSS36 ( ortholog_one2one )
Mouse_ Prss36 ( ortholog_one2one )
Pig_ PRSS36 ( ortholog_one2one )
Rat_ Prss36 ( ortholog_one2one )
Rabbit_ PRSS36 ( ortholog_one2one )
OhnologsTMPRSS6, PRSS21, TMPRSS5
ParalogsPRSS53
TissueNA
Tissue SpecificityExpressed in fetal kidney, skeletal muscle, liver, placenta and heart. Also expressed in tumor cell lines derived from lung and colon adenocarcinomas. {ECO:0000269|PubMed:15536082}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:15536082}. Note=Not attached to membranes.
Mouse PG classificationNA
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