Gene Information
Gene NameHSPC015
OrganismHomo sapiens (Human)
Gene Length337
Protein Namesm7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ96C86
Gene CardDCPS
Uniprot IDQ96C86
PfamPF05652
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityDetected in liver, brain, kidney, testis and prostate. {ECO:0000269|PubMed:12871939}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1ST0  (X-ray  1.90A  1ST4  (X-ray  2.02A  1XML  (X-ray  2.00A  1XMM  (X-ray  2.50A  3BL7  (X-ray  2.31A  3BL9  (X-ray  1.80A  3BLA  (X-ray  2.60A  4QDE  (X-ray  2.90A  4QDV  (X-ray  2.80A  4QEB  (X-ray  3.21A  5OSY  (X-ray  2.06A 
DBSNP rs11557735  rs137941190 
Subcellular location [CC]Cytoplasm. Nucleus. Note=Predominantly localized in the nucleus. Nucleocytoplasmic shuttling protein that can transiently enter the cytoplasm in mammalian cells in a XPO1/CRM1-dependent manner.
Mouse PG classificationNA
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