| Gene Information | |
|---|---|
| Gene Name | HSPB8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 196 |
| Protein Names | Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Protein kinase H11) (Small stress protein-like protein HSP22) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000152137 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UJY1 |
| Gene Card | HSPB8 |
| Uniprot ID | Q9UJY1 |
| Pfam | PF00011 |
| In ASD | no |
| Allosteric Prediction | no (-0.999913847) |
| Ortholog in Animals | Alpaca_ HSPB8 ( ortholog_one2one ) Dog_ HSPB8 ( ortholog_one2one ) GuineaPig_ HSPB8 ( ortholog_one2one ) Macaque_ HSPB8 ( ortholog_one2one ) Mouse_ Hspb8 ( ortholog_one2one ) Pig_ HSPB8 ( ortholog_one2one ) Rat_ Hspb8 ( ortholog_one2one ) Rabbit_ HSPB8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CRYAB, CRYAA, HSPB3, HSPB6, HSPB1, HSPB2, HSPB7, HSPB9 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in skeletal muscle and heart. {ECO:0000269|PubMed:11470154}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs55826713 rs1565927080 rs1565929080 rs104894351 rs1565929090 rs104894345 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19464326, ECO:0000269|PubMed:28144995}. Nucleus {ECO:0000269|PubMed:19464326}. Note=Translocates to nuclear foci during heat shock. |
| Mouse PG classification | LPG |
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