| Gene Information | |
|---|---|
| Gene Name | HSPB7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 170 |
| Protein Names | Heat shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000173641 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UBY9 |
| Gene Card | HSPB7 |
| Uniprot ID | Q9UBY9 |
| Pfam | PF00011 |
| In ASD | no |
| Allosteric Prediction | no (-1.321764053) |
| Ortholog in Animals | Alpaca_ HSPB7 ( ortholog_one2one ) Dog_ HSPB7 ( ortholog_one2one ) GuineaPig_ HSPB7 ( ortholog_one2one ) Macaque_ HSPB7 ( ortholog_one2one ) Mouse_ Hspb7 ( ortholog_one2one ) Pig_ HSPB7 ( ortholog_one2one ) Rat_ Hspb7 ( ortholog_one2one ) Rabbit_ HSPB7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CRYAB, CRYAA, HSPB3, HSPB6, HSPB1, HSPB2, HSPB8, HSPB9 |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is highly expressed in adult and fetal heart, skeletal muscle, and at a much lower levels in adipose tissue and in aorta. Undetectable in other tissues. Isoform 2 and isoform 3 are poorly detected in heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19464326}. Nucleus {ECO:0000269|PubMed:19464326}. Nucleus, Cajal body {ECO:0000269|PubMed:19464326}. Note=Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. |
| Mouse PG classification | NA |
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