| Gene Information | |
|---|---|
| Gene Name | HSPB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 182 |
| Protein Names | Heat shock protein beta-2 (HspB2) (DMPK-binding protein) (MKBP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000170276 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q16082 |
| Gene Card | HSPB2 |
| Uniprot ID | Q16082 |
| Pfam | PF00525; PF00011 |
| In ASD | no |
| Allosteric Prediction | no (-0.171091652) |
| Ortholog in Animals | Alpaca_ HSPB2 ( ortholog_one2one ) Dog_ HSPB2 ( ortholog_one2one ) GuineaPig_ HSPB2 ( ortholog_one2one ) Macaque_ HSPB2 ( ortholog_one2one ) Mouse_ Hspb2 ( ortholog_one2one ) Rat_ Hspb2 ( ortholog_one2one ) Rabbit_ HSPB2 ( ortholog_one2one ) |
| Ohnologs | HSPB6, CRYAA |
| Paralogs | CRYAB, CRYAA, HSPB3, HSPB6, HSPB1, HSPB8, HSPB7, HSPB9 |
| Tissue | heart, skeletal.muscle |
| Tissue Specificity | Expressed preferentially in skeletal muscle and heart but not in the lens. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001899(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 6F2R (X-ray 3.90A ) |
| DBSNP | rs4252589 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19464326}. Nucleus {ECO:0000269|PubMed:19464326}. Note=Localizes to nuclear foci. |
| Mouse PG classification | NA |
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