| Gene Information | |
|---|---|
| Gene Name | HSPA9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 679 |
| Protein Names | Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74) |
| Target Name | mortalin |
| Target Type | Clinical trial target |
| Gene Age | 1292 ( ENSG00000113013 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P38646 |
| Gene Card | HSPA9 |
| Uniprot ID | P38646 |
| Pfam | PF00012 |
| In ASD | no |
| Allosteric Prediction | yes (0.388250504) |
| Ortholog in Animals | Alpaca_ HSPA9 ( ortholog_one2one ) Dog_ HSPA9 ( ortholog_one2one ) GuineaPig_ HSPA9 ( ortholog_one2one ) Macaque_ HSPA9 ( ortholog_one2one ) Mouse_ Hspa9 ( ortholog_one2one ) Pig_ HSPA9 ( ortholog_one2one ) Rat_ Hspa9 ( ortholog_one2one ) Rabbit_ HSPA9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HSPA4L, HSPA6, HSPA1L, HSPH1, HSPA2, HSPA1A, HSPA1B, HSPA13, HSPA5, HSPA14, HSPA8, HYOU1, HSPA4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004872(Rat);0.045902(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3N8E (X-ray 2.80A ) 4KBO (X-ray 2.80A ) 6NHK (X-ray 2.78A ) 6P2U (X-ray 2.00A ) 6PMT (X-ray 2.30A ) |
| DBSNP | rs17856004 rs751478142 rs35091799 rs765368797 rs199715716 rs768283289 rs34558740 rs147723579 rs905439101 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:22002106, ECO:0000269|PubMed:26702583}. Nucleus, nucleolus {ECO:0000269|PubMed:22002106}. |
| Mouse PG classification | NA |
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