| Gene Information | |
|---|---|
| Gene Name | MEIOB |
| Organism | Homo sapiens (Human) |
| Gene Length | 442 |
| Protein Names | Meiosis-specific with OB domain-containing protein (EC 3.1.-.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000162039 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N635 |
| Gene Card | MEIOB |
| Uniprot ID | Q8N635 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.186809192) |
| Ortholog in Animals | Alpaca_ MEIOB ( ortholog_one2many ) Dog_ MEIOB ( ortholog_one2many ) Macaque_ MEIOB ( ortholog_one2many ) Mouse_ Meiob ( ortholog_one2many ) Rat_ Meiob ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis |
| Tissue Specificity | In fetal gonads, specifically expressed in the ovary starting at the 14th weeks post fertilization (PubMed:24068956). In the adult, restricted to testis (PubMed:28206990). {ECO:0000269|PubMed:24068956, ECO:0000269|PubMed:28206990}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1742446 rs1555472691 rs1657125 rs9806945 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q9D513}. Nucleus {ECO:0000250|UniProtKB:Q9D513}. Chromosome {ECO:0000250|UniProtKB:Q9D513}. Note=Co-localizes with the RPA complex on meiotic chromosome axes. Accumulates on resected DNA. Localization is dependent on SPATA22. {ECO:0000250|UniProtKB:Q9D513}. |
| Mouse PG classification | NA |
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