| Gene Information | |
|---|---|
| Gene Name | HSPA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 639 |
| Protein Names | Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) |
| Target Name | heat shock-related 70 kda protein 2 |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000126803 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P54652 |
| Gene Card | HSPA2 |
| Uniprot ID | P54652 |
| Pfam | PF00012 |
| In ASD | no |
| Allosteric Prediction | yes (1.111448536) |
| Ortholog in Animals | Alpaca_ HSPA2 ( ortholog_one2one ) Dog_ HSPA2 ( ortholog_one2one ) GuineaPig_ HSPA2 ( ortholog_one2one ) Mouse_ Hspa2 ( ortholog_one2one ) Rat_ Hspa2 ( ortholog_one2one ) Rabbit_ HSPA2 ( ortholog_one2one ) |
| Ohnologs | HSPA1B, HSPA1A, HSPA1L |
| Paralogs | HSPA4L, HSPA6, HSPA1L, HSPH1, HSPA1A, HSPA1B, HSPA9, HSPA13, HSPA5, HSPA14, HSPA8, HYOU1, HSPA4 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.010256(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 3I33 (X-ray 1.30A ) 4FSV (X-ray 1.80A ) 5FPD (X-ray 1.97A ) 5FPE (X-ray 1.96A ) 5FPM (X-ray 1.96A ) 5FPN (X-ray 1.96A ) |
| DBSNP | rs45456191 rs45447398 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:P17156}. Note=Colocalizes with SHCBP1L at spindle during the meiosis process. {ECO:0000250|UniProtKB:P17156}. |
| Mouse PG classification | NA |
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