| Gene Information | |
|---|---|
| Gene Name | PTX3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 381 |
| Protein Names | Pentraxin-related protein PTX3 (Pentaxin-related protein PTX3) (Tumor necrosis factor alpha-induced protein 5) (TNF alpha-induced protein 5) (Tumor necrosis factor-inducible gene 14 protein) (TSG-14) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000163661 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P26022 |
| Gene Card | PTX3 |
| Uniprot ID | P26022 |
| Pfam | PF00354 |
| In ASD | no |
| Allosteric Prediction | yes (0.637403803) |
| Ortholog in Animals | Alpaca_ PTX3 ( ortholog_one2one ) GuineaPig_ PTX3 ( ortholog_one2one ) Macaque_ PTX3 ( ortholog_one2one ) Mouse_ Ptx3 ( ortholog_one2one ) Pig_ PTX3 ( ortholog_one2one ) Rat_ Ptx3 ( ortholog_one2one ) Rabbit_ PTX3 ( ortholog_one2one ) |
| Ohnologs | NPTX2 |
| Paralogs | CRP, APCS, PTX4, NPTX1, NPTX2 |
| Tissue | bone.marrow |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002101(Rat);0.018182(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7ZL1 (EM 2.50A ) |
| DBSNP | rs34655398 rs3816527 rs35415718 rs4478039 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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