Gene Information
Gene NameHSPA10
OrganismHomo sapiens (Human)
Gene Length646
Protein NamesHeat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP11142
Gene CardHSPA8
Uniprot IDP11142
PfamPF00012
In ASDyes
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:11276205}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3AGY  (X-ray  1.85A  3AGZ  (X-ray  2.51A  3ESK  (X-ray  2.05A  3FZF  (X-ray  2.20A  3FZH  (X-ray  2.00A  3FZK  (X-ray  2.10A  3FZL  (X-ray  2.20A  3FZM  (X-ray  2.30A  3LDQ  (X-ray  1.90A  3M3Z  (X-ray  2.10A  4H5N  (X-ray  1.86A  4H5R  (X-ray  1.64A  4H5T  (X-ray  1.90A  4H5V  (X-ray  1.75A  4H5W  (X-ray  1.94A  4HWI  (X-ray  2.27A  4KBQ  (X-ray  2.91A  5AQF  (X-ray  1.88A  5AQG  (X-ray  2.24A  5AQH  (X-ray  2.00A  5AQI  (X-ray  1.98A  5AQJ  (X-ray  1.96A  5AQK  (X-ray  2.09A  5AQL  (X-ray  1.69A  5AQM  (X-ray  1.63A  5AQN  (X-ray  2.45A  5AQO  (X-ray  2.12A  5AQP  (X-ray  2.08A  5AQQ  (X-ray  2.72A  5AQR  (X-ray  1.91A  5AQS  (X-ray  2.00A  5AQT  (X-ray  1.90A  5AQU  (X-ray  1.92A  5AQV  (X-ray  1.75A  6B1I  (X-ray  2.30A  6B1M  (X-ray  1.90A  6B1N  (X-ray  1.80A  6ZYJ  (X-ray  1.85A 
DBSNP rs11551602  rs11551598 
Subcellular location [CC]Cytoplasm. Melanosome. Nucleus, nucleolus. Cell membrane. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock.
Mouse PG classificationNA
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