| Gene Information | |
|---|---|
| Gene Name | HSH2D |
| Organism | Homo sapiens (Human) |
| Gene Length | 352 |
| Protein Names | Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000196684 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96JZ2 |
| Gene Card | HSH2D |
| Uniprot ID | Q96JZ2 |
| Pfam | PF00017 |
| In ASD | no |
| Allosteric Prediction | no (-0.491645296) |
| Ortholog in Animals | Alpaca_ HSH2D ( ortholog_one2one ) Dog_ HSH2D ( ortholog_one2one ) Macaque_ HSH2D ( ortholog_one2one ) Mouse_ Hsh2d ( ortholog_one2one ) Pig_ HSH2D ( ortholog_one2one ) Rat_ Hsh2d ( ortholog_one2one ) Rabbit_ HSH2D ( ortholog_one2one ) |
| Ohnologs | SH2D7 |
| Paralogs | SH2D4A, SH2D2A, SH2D7, SH2D4B |
| Tissue | spleen, whole.blood |
| Tissue Specificity | Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta. {ECO:0000269|PubMed:11700021, ECO:0000269|PubMed:12960172}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2CS0 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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