| Gene Information | |
|---|---|
| Gene Name | MS4A7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 240 |
| Protein Names | Membrane-spanning 4-domains subfamily A member 7 (CD20 antigen-like 4) (CD20/FC-epsilon-RI-beta family member 4) (Four-span transmembrane protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000166927 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9GZW8 |
| Gene Card | MS4A7 |
| Uniprot ID | Q9GZW8 |
| Pfam | PF04103 |
| In ASD | no |
| Allosteric Prediction | no (-1.351767156) |
| Ortholog in Animals | Alpaca_ MS4A7 ( ortholog_one2one ) Dog_ MS4A7 ( ortholog_one2one ) Macaque_ MS4A7 ( ortholog_one2one ) Mouse_ Ms4a7 ( ortholog_one2one ) Pig_ MS4A7 ( ortholog_one2one ) Rat_ Ms4a7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MS4A12, MS4A6E, MS4A6A, MS4A10, MS4A2, MS4A1, MS4A8, MS4A15, TMEM212, MS4A13, MS4A5, MS4A18, MS4A4E, MS4A4A, MS4A3, MS4A14 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous expression in normal tissues. Expression is more elevated in adult liver, lung, spleen, and heart than in their fetal counterparts, and is higher in normal tissues than in the cancerous tissue or cell lines. Low levels of expression were detected in the promonocytic stage, whereas high levels of expression were detected in mature monocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2233241 rs2233249 rs2233251 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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