Gene Information
Gene NameHSF2
OrganismHomo sapiens (Human)
Gene Length536
Protein NamesHeat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000025156 )
Evolutionary StageEukaryota
AlphaFoldDBQ03933
Gene CardHSF2
Uniprot IDQ03933
PfamPF00447; PF06546
In ASDno
Allosteric Predictionno (-0.702256797)
Ortholog in AnimalsAlpaca_ HSF2 ( ortholog_one2one )
Dog_ HSF2 ( ortholog_one2one )
GuineaPig_ HSF2 ( ortholog_one2one )
Macaque_ HSF2 ( ortholog_one2one )
Mouse_ Hsf2 ( ortholog_one2one )
Pig_ HSF2 ( ortholog_one2one )
Rat_ Hsf2 ( ortholog_one2one )
Rabbit_ HSF2 ( ortholog_one2one )
OhnologsHSF1
ParalogsHSF4, HSF1, HSFX2, HSFX1, HSF5, HSFY2, HSFY1, HSFX4, HSFX3
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5D8K  (X-ray  1.73A  5D8L  (X-ray  2.07A  5HDK  (X-ray  1.32A  7DCI  (X-ray  1.70A  7DCU  (X-ray  1.75A 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:8339932}. Nucleus {ECO:0000269|PubMed:8339932}. Note=Cytoplasmic during normal growth and moves to the nucleus upon activation.
Mouse PG classificationNA
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